- Product Details
Keywords
- Boc-NH-PEG5-CH2COOH
Quick Details
- ProName: BocNH-PEG5-acid
- CasNo: 890152-41-7
- Molecular Formula: C17H33NO9
- Application: This heterobifunctional, PEGylated cro...
- PackAge: 250MG,1G
- LimitNum: 0
Superiority
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG5-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTACs) for targeted protein degradation.