- Product Details
Keywords
- H2N-PEG4-CH2CH2COOtBu
- H2N-dPEG(4)-CO-OtBu
Quick Details
- ProName: Amino-PEG4-t-butyl ester
- CasNo: 581065-95-4
- Molecular Formula: C15H31NO6
- Application: This heterobifunctional, PEGylated cro...
- PackAge: 250MG,1G
- LimitNum: 0
Superiority
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTACs) for targeted protein degradation.