- Product Details
Keywords
- HO-PEG5-CO-OtBu
Quick Details
- ProName: Hydroxy-PEG5-t-butyl ester
- CasNo: 850090-09-4
- Molecular Formula: C17H34O8
- Application: This heterobifunctional, PEGylated cro...
- PackAge: 250MG,1G
- Purity: >=95%
- LimitNum: 0
Superiority
This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTACs) for targeted protein degradation.