- Product Details
Keywords
- H2N-PEG5-CH2CH2COOtBu
Quick Details
- ProName: Amino-PEG5-t-butyl ester
- CasNo: 1446282-18-3
- Molecular Formula: C17H35NO7
- Application: This heterobifunctional, PEGylated cro...
- PackAge: 250MG,1G
- Purity: >=95%
- LimitNum: 0
Superiority
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTACs) for targeted protein degradation.