- Product Details
Keywords
- Propargyl-PEG4-CH2CO2H
Quick Details
- ProName: Propargyl-PEG4-acid
- CasNo: 1415800-32-6
- Molecular Formula: C12H20O6
- Application: This heterobifunctional, PEGylated cro...
- PackAge: 250MG,1G
- LimitNum: 0
Superiority
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTACs) for targeted protein degradation.